Skip to content

Etizolam Use Surges as Unapproved Xanax Alternative

Etizolam, also known as thienodiazepine, is related to a class of substances known as benzodiazepines. Typically sold in a powder or tablet form, etizolam has gained prominence in the illicit drug market in recent years due to its similarity to other popular benzodiazepines, or "benzos," such as Xanax and Valium. Etizolam was originally developed for the treatment of anxiety, depression, and insomnia, and is considered a legitimate pharmaceutical product in Japan, India, and Italy. However, this substance has not been approved for any form of medical use in the US by the FDA. As such, it poses a substantial risk to card brands and is of increasing concern to regulatory agencies.

Although it is not permitted for human consumption in the US, etizolam is frequently abused by US-based consumers, who purchase the compound for its powerful sedative effects. It can take the form of a powder, tablet, or spiked blotter paper. Many online vendors appear to sell foreign-manufactured tablets that likely either ship from outside the US or have entered the US through unofficial channels. Foreign brand names include Etilaam, Etizest, Depas, Etizola, Sedekopan, and Pasaden.

What consumers may not realize is that etizolam also carries risk of dependency, toxicity, and fatal overdose, particularly when combined with other central nervous system depressants. One young man, Adam Hunt, reportedly took etizolam he bought online and was later discovered unconscious by his mother. Hunt died after spending four days in a medically induced coma. Given the ease of purchasing it online, it is no surprise that etizolam has been increasingly prominent in online drug forums.

An etizolam vendor markets Etizest and other India-manufactured etizolam products.

One such website, shown above, offers a small catalog of etizolam tablets marketed as "research chemicals." The website states that it does not sell etizolam to anyone who is not a "research institution," yet features no safeguards or verification which prevent purchases by individuals. While marketed as "not for human consumption," the merchant has a Reddit account and frequently interacts with user inquiries about purchasing etizolam, ultimately directing traffic to their website. See the screenshot below.

A Reddit user promotes their etizolam website on a forum popular with recreational users.

The use of Reddit for advertising the sale of illicit substances is a common practice among "research chemical" websites. This pattern of deceptive marketing around "research chemicals" is familiar to LegitScript's analysts, and they use a variety of tools and resources to identify a website operator's intent.

Payment service providers should be cautious of any website marketing etizolam, even if it appears to be for research purposes. Searching the internet for an operator's online footprint outside of the website can give important clues as to the operator's true intent. Partner with the experts at LegitScript to reduce your risk of merchants who are selling unapproved drugs or who are engaging in one of dozens of other high-risk categories LegitScript monitors. Contact us to learn more.

 

Recent Blog Articles

Why LegitScript Certification Is Your Passport in 2025: A Recap for Healthcare Businesses

In a dynamic regulatory landscape where risk, reputation, and compliance increasingly determine access to financial services, healthcare businesses face a unique challenge. A recent webinar hosted by LegitScript - featuring Rob Bast, chief sales officer at Corepay, and Angela Salter, director of sal...

LegitScript & Special Guest Marketplace Risk Panel Recap: How to Stay Ahead of Global Regulations and Trends: Using Deep Intelligence to Shape Policy and Mitigate Risk

At Marketplace Risk, experts tackled the challenges of content moderation and platform responsibility, focusing on drug-related content, evolving evasion tactics, and the balance between AI and human oversight. Transparency and proactive safety measures took center stage. Listen below to an excerpt...
FDA updates REMS program for common abortion drug mifepristone.

Key Takeaways from LegitScript’s Webinar: Navigating Risks and Regulations in Online Abortion Pill Sales

The online sale of abortion medication is at the center of a rapidly evolving regulatory and risk environment. In LegitScript's June 2025 webinar, Online Abortion Pill Sales: Navigating Regulations and Problematic Activity, experts outlined how recent legal changes are reshaping access to medication...

Merchant Onboarding Essentials: What You Need to Know

Modern merchant onboarding involves much more than collecting documents - it's about building a smart, scalable risk management process that can keep up with changing technology and fraud tactics. Whether you're launching a payments platform or refining your underwriting approach, getting onboarding...